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This study successfully demonstrated an innovative method to fabricate biosorbents from abundant and renewable natural polymers (cellulose and chitosan) for dispatching metal ions from water.Antibacterial and wound healing-promoting effect of sponge-like chitosan-diluted silver nanoparticles biosynthesized by iturin.Silver nanoparticles (AgNPs) are widely used in wound dressing, but are circumscribed in the application due to its high toxicity at effective densenessses. iturin-AgNPs was previously bumped to have much higher antibacterial activity at lower AgNPs content than the commercial AgNPs. To verify its potential application in the promotion of wound healing, a chitosan (CS) composite sponge dressing-loaded iturin-AgNPs was educated and appraised for their antibacterial activity in vitro and used for wound healing in vivo. As  aloe emodin structure , the synthesized CS dressing had high porosity and water absorption.

As beared, the antibacterial activity of CS dressing was significantly promoted by the incorporation of iturin-AgNPs. The CS dressing-diluted iturin-AgNPs demonstrated more effective inhibition of bacterial infection and promotion of wound healing processing and quality than the commercial wound garbing stretched AgNPs in vivo.  aloe emodin cancer  for the promotion of wound healing by the CS dressing-laded iturin-AgNPs were recovered as the enhancement of re-epithelialization and collagen formation, as well as the increased antibacerial activity. No toxicity was geted to all harmoniums of mice. The study prepared an efficient way to enhance the antibacterial activity of CS dressing loaded AgNPs at low toxicity, which has great potential in wound care application.enquiring the Impact of Collagen-Chitosan deduced from Scomberomorus Guttatus and Shrimp Skin on Second-Degree Burn in Rats Model.BACKGROUND: The present study focused on burning as one of the main causas of mortality with detrimental economic and social issues in the world.

The purpose of this study was to investigate the impact of collagen-chitosan gel pulled from Scomberomorus guttatus and shrimp skin in the treatment of second degree burn healing among rats. MATERIALS & METHOD: To fulfill the purpose of the study, chitosan and collagen were pulled respectively from shrimp and Scomberomorus guttatus skin waste by the acid-finded method and were evaluated by habituating Pico Tag, SDS-PAGE. The burn wraped healing efficiency of marine collagen-chitosan gel was probed in vivo using rats. Three different proportions of collagen and chitosan blend (Col-CH, 1:3, 1:1 and 3:1) were developed to obtain the most effective Col-CH gel for burn wound healing and were compared to the faunas handled with silver sulfadiazine ointment. Healing burn wound was readed by measuring wound surface area with Image J and histopathologic examination was carried out grinded on the mean of epithelialization, fibroblastic cubicles, acute and chronic inflammatory cells, angiogenesis, structure collagen and the amount of collagen on days 15 and 25 post-burn The consequences of SDS-PAGE designated that the educed collagen was type I and it was composed of two α (α(1) and α(2)) chains. Amino acid analysis designated a much higher glaycin content in evoked collagen which comed to one-third of the total amino. The wound surface measurement showed a significant reduction in wound size in the group treated with Col-CH (3:1) equated to silver-sulfadiazine processed group on 15th and 25th days.

Histopathological determinations exemplifyed a high score in epithelialization, collagen, collagen structure, fibroblast cell and a decrease in inflammatory cells infiltration in Col-CH (3:1) regaled group on 25th day. The most obvious finding of the present study is that chitosan-collagen gel (3:1) played a better efficacy compared to sulfadiazine in burn wound healing on day 25 post-burn.Therapeutic efficacy of chitosan nanoparticles diluted with BCG-polysaccharide nucleic acid and ovalbumin on airway inflammation in asthmatic mice.In this study, immunoregulation and desensitization therapies were jointly practiced in the treatment of asthma, in which chitosan (CS) nanoparticles were used. BALB/c mice were selected and mouse modelings of asthma were manufactured.